منابع مشابه
Hypoxia. 5. Hypoxia and hematopoiesis.
Our understanding of organismal responses to hypoxia has stemmed from studies of erythropoietin regulation by hypoxia that led to the discovery of the master regulator of the hypoxic response, i.e., hypoxia-inducible factor (HIF). This is a transcription factor that is now known to induce the expression of a battery of genes in response to hypoxia. HIF-1 and HIF-2 regulate many genes that are i...
متن کاملHypoxia. Hypoxia, hypoxia inducible factor and myeloid cell function
With little in the way of effective therapeutic strategies to target the innate immune response, a better understanding of the critical pathways regulating neutrophil and macrophage responses in inflammation is key to the development of novel therapies. Hypoxia inducible factor (HIF) was originally identified as a central transcriptional regulator of cellular responses to oxygen deprivation. Ho...
متن کاملFlaxseed Can Reduce Hypoxia-Induced Damages in Rat Testes
Introduction: Hypoxia is a common leading cause of detrimental effect on structure and function of tissue during increase in the production of reactive oxygen species that are generated during the re-oxygenation phase of intermittent continuous hypobaric hypoxia and contribute to physiological responses. This study was carried out to evaluate the effects of flaxseed (Fx) in reducing the inciden...
متن کاملHypoxia
Dr. Van Liere's earlier book on this subject* was probably the first detailed study of the biology of low oxygen pressure. Investigations of the effect of high altitude, using mountain climbing or balloon ascent as a tool, go back to the late eighteenth century, but the major impetus seems to have been the need for military aviation in World War I. This interest was maintained until about 1935 ...
متن کاملEFFECTS OF HYPOXIC HYPOXIA AND CARBON MONOXIDE-INDUCED HYPOXIA ON THE CARDIOVASCULAR SYSTEM AND REGIONAL BLOOD FLOW OF THE ANESTHETIZED CAT
The purpose of this study was to investigate the potential responses of the cardiovascular system and regional blood flow to hypoxic hypoxia (BB) and to carbon monoxide (CO)-induced hypoxia (COH). Ten anesthetized cats were studied under two nonnoxic (control: CONT) and two hypoxic conditions. Four types of radioactive micro spheres were used to measure regional blood flow during CONT an...
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ژورنال
عنوان ژورنال: Southern African Journal of Anaesthesia and Analgesia
سال: 2020
ISSN: 2220-1173,2220-1181
DOI: 10.36303/sajaa.2020.26.6.s3.2563